HISTOPLASMA CAPSULATUM

Causative organism of Histoplasmosis
The Organism Histoplasma spores
Histoplasma capsulatum conidia
Image kindly supplied by Tom Volk of the University of Wisconsin-La Crosse

Tom Volks Fungi
Histoplasma yeast
Histoplasma capsulatum yeast
Image kindly supplied by Tom Volk of the University of Wisconsin-La Crosse

Tom Volks Fungi

THE ORGANISM
Dimorphic yeast-mold fungus
Produces infective conidia - the infective agent in the lungs
Yeast phase found throughout infection in body
Bats are naturally infected with Histoplasma, often having intestinal lesions

grows as a mold in nature or when cultured at room temperature but converts to a small (1 to 5 µm in diameter) yeast cell at 37° C (98.6° F) and when invading host cells.

WHERE IS IT FOUND?
It is a saphrotroph found in warm moist soil contaminated with bird droppings
e.g. chicken coops, caves, old buildings and nesting areas
The spores produced become airborne when the soil dries and is disturbed
Found throughout the world, endemic in some parts of the US
and Asia
Histoplasmosis
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