SPOROTRICHOSIS

The Organism ORGANISM
Dimorphic fungus Sporothrix schenkii
Found on living plants, soil, plant debris, compost, timber, hay

Entry to the body ENTRY TO THE BODY
Puncture wound from a thorn or splinter contaminated with the fungus

Clinical Features CLINICAL FEATURES
After an incubation period (1 to 12 weeks) a red papule (bump) arises
This resembles a boil
This ulcerates, forming an open sore
New lesions occur along the lymph channels
Each of these may open into another ulcerated sore.
Can remain localised or spread throughout body.
Affects joints, and lungs, creating cavities in the lungs which lose function.

Riskgroups RISK GROUPS
Florists, gardeners, foresters at highest risk
This form usually strikes men who have alcoholism or individuals with a condition which weakens the immune system

Incidence and Global Distribution INCIDENCE AND GLOBAL DISTRIBUTION
Disease occurs throughout the world
Most common subcutaneous mycotic disease in US.
Commonest in alcoholic males
Or those with weakened immunity

Diagnosis DIAGNOSIS
Culture the fungus from pus or fluid from an ulcerated sore
culture from other infected areas, e.g. joint.

Treatment and Prevention TREATMENT AND PREVENTION
If untreated, symptoms may come and go for years.
When treated, the cure rate is high..
Oral anti-fungal agent itraconazole or potassium iodide solution drink
Amphotericin B via IV in severe cases
Wearing gloves and long sleeves when working risk materials.


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